Welcome to the Marty Lab

Research in the Marty Lab is centered on characterization of membrane proteins by mass spectrometry. Our lab works at the interface of chemistry and biochemistry, combining cutting-edge analytical methodologies with biotechnology.

News

National Institutes of Health MIRA Award

Congratulations to Prof. Marty on being awarded the National Institutes of Health/National Institute of General Medical Sciences Maximizing Investigator's Research Award (MIRA) R35 GM128624! This grant will support the lab efforts to employ native mass spectrometry and nanodiscs to understanding membrane protein-lipid interactions.

Congrats to Dane and Jessica on Graduating

Congratulations to Dane Zambrano and Jessica Diesing on their graduation and successful completion of their undergraduate theses. Jessica was also recently awarded the CBC Outstanding Peer Mentor Award and CBC Student of the Month. Congrats!

American Society for Mass Spectrometry Research Award

Congratulations to Prof. Marty on being awarded one of the 2018 ASMS Research Awards! Thanks to Thermo Fisher for sponsoring the award.

New Article in Journal of the American Society for Mass Spectrometry

Check out our new article on MetaUniDec, software for high throughput deconvolution of native mass spectra:

Reid, D. J.; Diesing, J. M.; Miller, M. A.; Perry, S. M.; Wales, J. A.; Montfort, W. R.; Marty, M. T. MetaUniDec: High-Throughput Deconvolution of Native Mass Spectra. J. Am. Soc. Mass. Spectrom. 2018, DOI: 10.1007/s13361-13018-11951-13369.

The software can be downloaded from links in the software tab. Happy deconvolving!

Congrats to Dane Zambrano

Undergrad, Dane Zambrano, has been with the Marty Lab since Day 1. She is graduating soon and has garnered some of the top awards from the CBC department, including the Excellence in Undergraduate Research Award. Congrats to Dane and good luck in grad school at UW Seattle!

https://cbc.arizona.edu/spotlight/dane-zambrano-wins-cbc-excellence-undergraduate-research-award

New Article in Analytical Chemistry

Check out our new article describing engineering of nanodiscs for native mass spectrometry.

Reid, D.J.; Keener, J.E.; Wheeler, A.P.; Zambrano, D.E.; Diesing, J.M.; Reinhardt-Szyba, M.; Makarov, A.A.; Marty, M.T. "Engineering Nanodisc Scaffold Proteins for Native Mass SpectrometryAnal. Chem. 2017, DOI: 10.1021/acs.analchem.7b03569

Plasmids used in this study can be acquired from Addgene: http://www.addgene.org/Michael_Marty/

Bisgrove Scholar Award

Congratulations to Prof. Marty on being awarded the Bisgrove Scholar Award from Science Foundation Arizona. For more information, take a look at this article.

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New Review Article

A review of membrane mimetics for mass spectrometry was recently published in Accounts of Chemical Research. For those interested in learning more about our research, this is a great place to start.

Marty, M.T.; Hoi, K.K.; Robinson, C.V. "Interfacing Membrane Mimetics with Mass Spectrometry" Acc. Chem. Res. 2016, DOI: 10.1021/acs.accounts.6b00379